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BULLDOG HEALTH TESTING

CMR1, DM, HUU

This article, written by myself, is also found on The CBCA website under Health.
 
OUR CONTRIBUTION
Rare Bulldogs has started its Health Testing in early 2017. This is an ongoing process that will take several years to complete. As per our Geneticists recommendations, we will not take our affected bulldogs out of our breeding programs as this would be very detrimental to the breed as a whole....our breed is already in trouble as you will see in the article referenced below, PLEASE read it! Therefore, we will start with our keep back babies for our program, striving to keep breeders that are clear or at the very least, only carriers of the 3 disease genes mentioned here. If we ALL do this, we will bring back our breed. Our Breed is in so much trouble, that scientists are calling the English Bulldog Breed a DEAD END!
 
 

Rare Bulldogs considers it our duty to protect the Bulldog/English Bulldog, our very special breed. Most consider the Bulldog an unhealthy breed. We do not. When ethical, knowledgeable breeders use healthy dogs in their programs, the outcome is healthier puppies overall. Our breed Standard reflects necessary qualities needed to produce healthier puppies in our breed.

As many may know, there has been a recent Study in the genetic diversity done on the Bulldog Breed that is rather alarming. We, as CBCA Rare Color Breeders are honored to say that we have made large strides in hopefully improving on this study. In the last 10 years, because of the diversity in adding the Rare Colors to our breeding programs, most Rare Color Breeders have seen a significant difference in the overall health of puppies produced, some in less than 3 years.

 

HEALTH IN GENETIC TESTING
Like all breeds there may be some health issues related to the Bulldog breed. Because they are a brachycephalic breed, bulldogs will often have breathing problems which are related to their elongated soft-palate blocking their airways. If this were to become a chronic problem, surgery may be an option. Other health issues reported in bulldogs are cherry eye & skin infections which can be easily treated by cleaning the skin-folds regularly. Some Bulldogs will be faced with health issues in their lives as are all dogs, but the majority of well-bred Bulldogs are healthy dogs. Work with a responsible breeder, gain the education you need about specific health concerns within the breed. 

CMR1, DM, HUU
 
CMR1
More Info

Canine Multifocal Retinopathy (CMR), a recessive eye disorder, is known to affect several breeds including the English Bulldog. This causes raised lesions that form on the retina and alters the appearance of the eye but usually does not affect sight. These lesions, looking somewhat like blisters, vary in location and size. Typically they are present in both eyes of the affected dog. Lesions may disappear, or may result in minor retinal folding. Symptoms usually appear when a puppy is only a few months old, and generally do not worsen over time.

Since CMR1 is recessive, both parents would need to be carriers of the mutation to produce an affected puppy. Breeding two unaffected or one unaffected and one carrier will not produce affected offspring. However if one parent is a carrier, a percentage of the offspring will be carriers. It is necessary to test for the presence of the CMR mutation before breeding, so as not to breed two carriers together, and unwittingly produce a fully affected puppy. Dogs have two copies of the mutation are susceptible to develop retinal deformation, although fully affected dogs do not always develop into disease.

In most cases, treatment is not required.

Ethical breeding practices with this disorder:

No restrictions on unaffected dogs.
No restrictions with an unaffected to a carrier. If your breeding dog is a carrier, it is a must to test the intended mate to be unaffected.
Restriction on breeding two carriers.
Restriction on breeding fully affected to a carrier. Intended mates to fully affected should be clear.

 
DM
More Info
 

Degenerative myelopathy (DM) is a progressive disease of the spinal cord in older dogs, onset typically between 8 and 14 years of age.

It begins with a loss of coordination (ataxia) in the hind limbs. The affected dog will wobble when walking, knuckle over or drag the feet. As the disease progresses, the dog's hind legs will weaken and eventually the dog will be unable to walk at all, and can experience loss of urinary and fecal continence with eventual weakness in the front limbs. Fortunately, there is no direct pain associated with Degenerative Myelopathy.

A small percentage of dogs that have inherited two copies of the mutation will not experience symptoms at all. Thus, this disease is not completely penetrant, meaning the disease does not affect every dog that has the genotype.

Ethical breeding practices with this disorder:

No restrictions on unaffected dogs.
No restrictions with an unaffected to a carrier. If your breeding dog is a carrier, it is a must to test the intended mate to be unaffected.
Restriction on breeding two carriers.
Restriction on breeding fully affected to a carrier. Intended mates to fully affected should be clear.

 
HUU
More Info
 

The Hyperuricosuria mutation is autosomal recessive. Both parents will need to be carriers of the mutation to pass it on to their offspring. Only individuals that have two copies of the mutation, have a higher risk of developing clinical signs of the disease. Carriers of only one copy of the mutation will not develop the disease.

Dogs with this genetic mutation metabolize waste products as uric acid in their urine, this condition that predisposes dogs to bladder stones that can result in urinary obstruction. The uric acid forms into hard stones in the bladder, causing pain and inflammation as the stone moves through the urinary tract.

A dog that has difficulty urinating or appears to have an inflamed bladder may have HUU. Other signs can include blood in the urine and frequent urination. If the dog is unable to pass the urate stones without medical intervention, surgery is required to remove them. If the urinary tract is blocked, the condition can be life threatening. HUU is uncomfortable and painful for the dog.

Carriers will not show any symptoms of HUU. Affected dogs may not show any signs, so it is important to test dogs for HUU prior to breeding.

Ethical breeding practices with this disorder:

No restrictions on unaffected dogs.
No restrictions with an unaffected to a carrier. If your breeding dog is a carrier, it is a must to test the intended mate to be unaffected.
Restriction on breeding two carriers.
Restriction on breeding fully affected to a carrier. Intended mates to fully affected should be clear.

Author: Alesia Dixon

Read the study: https://cgejournal.biomedcentral.com/articles/10.1186/s40575-016-0036-y

What Science Alert had to say about the study. Personally, I bet if the study was done on our Rare Colors, the findings would be vastly different.
ttp://www.sciencealert.com/english-bulldogs-are-at-a-genetic-tipping-point-study-finds

Good Information for you and your New Family Member
PLEASE send us your requests for more articles
 
Article 1: Pet Loss-when to get a new dog

Article 2: Household items that are dangerous to your dog

Article 3: Second Hand Smoke and your dog

Article 4: Vacationing with your Dog

Article 5: Take It Inside - Indoor Fun For Your Dog

Article 6: Take It Inside - Indoor Fun For Your Dog
Part 2

Article 7: Heat Stroke

Article 8: Does My Dog Really Have to Visit a Dentist

Article 9: Dog Chiropractic Practices

Article 10: The Toes Have It-Grooming Nails & Feet
Article 11: Proofing Your Home For Your New Bulldog

Article 12: Why Dogs Bark and What You Can Do About It

Article 13: House Training on the Go 2

Article 14: Dog Film Stars Part 1

Article 15: Symptoms, Prevention, and Treatment of Hip Dysplasia

Article 16: Bringing your dog to a Park is Always a Good Idea

Article 17: Table Food and Excessively Treating your Dog

Article 18: Achieving the Right Balance in Dog Food

Article 19: Stenotic Nares (Pinched Nostrils)


Article 20: Health benefits of Owning a Dog

Article 21: Shock Collars: Are They Safe or Cruel?
Bulldogs & Drowning
I have had Parents tell me that their bully can swim fine, and some can, up to between 1 and 2 years of age. Sad to say, those parents lost their bullys to drowning. You may wonder...what happened? Bullys, as they grow, tend to get more dense, thicker bones and dense muscles, and start to be what I call "Heavy Boned". A lot of times this does not occur until after 1 year of age, thus the sad scenario above....the bully could swim fine until one day it sank and drowned. NEVER take a chance!! It is definitely NOT worth it.
 
This is the ONLY SAFE way to have your Bully around or in the water!!! Even if they can swim, don't EVER take a chance.
Thank you Andria for doing it right!! Meet Lana Greene
 
 
 
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